Ledipasvir Actone /PVP

Ledipasvir Actone /PVP

API’s Name:Ledipasvir Actone /PVP

CAS No.:1256388-51-8

Indication:HCV

Innovator

Specification:In-House

US DMF:√

EU DMF

CEP

Only for R&D purpose

Product Detail

Intermediates

Code

CAS

Specification

LPSM1

1256387-87-7

In-House

LPSM1-5

291775-59-2

In-House

LPSM2

1129634-44-1

In-House

LPS-6

1441670-89-8

In-House


Ledipasvir acetone (GS-5885 acetone) is the active ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.


In Vitro

Ledipasvir acetone is considered the active ingredient, which is converted to Ledipasvir spray-dried dispersion, an amorphous free base.


Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Description

Ledipasvir acetone (GS-5885 acetone) is the active ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.


In Vitro

Ledipasvir acetone is considered the active ingredient, which is converted to Ledipasvir spray-dried dispersion, an amorphous free base.


Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Chemical structure

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